Neuroanatomy in Clinical Practice for Psychiatrists by Andrew M. Lerner, MD

Neuroanatomy in Clinical Practice for Psychiatrists

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Every psychiatric symptom has an address in the brain — and the clinician who can find it diagnoses faster, treats more precisely, and explains illness to patients in ways that change how they engage with care. Without that anatomical grounding, the psychiatrist is pattern-matching against a symptom checklist, missing the frontotemporal dementia behind the "treatment-resistant depression," the anti-NMDA receptor encephalitis behind the "first psychotic break," the akathisia behind the suicidal ideation that worsened after the antipsychotic was increased. Neuroanatomy in Clinical Practice for Psychiatrists gives you the circuit-level framework to move from symptom to structure to mechanism to treatment decision — at the bedside, in real time, with a patient in the chair. INSIDE THIS BOOK • The Circuit-to-Symptom System — a structured five-slot callout in every chapter that walks each major neural circuit forward to the exact psychiatric symptom it produces when it fails, so localization becomes automatic rather than effortful • The three prefrontal syndromes mapped and distinguished — dysexecutive, disinhibited, and apathetic presentations decoded at the bedside so you stop missing the frontal process hiding behind the mood disorder • The four dopaminergic pathways as a clinical tool — read every antipsychotic's full therapeutic and adverse profile, pathway by pathway, rather than memorizing side effects as arbitrary facts • The amygdala-prefrontal fear circuit explained fully — understand why exposure therapy works, when it will not, and how to optimize the biological conditions that make extinction learning possible before starting trauma-focused work • White matter and vascular depression — recognize why late-life depression with confluent white matter hyperintensities resists pharmacotherapy, and why vascular risk-factor management belongs in the treatment plan • Neuromodulation anatomy demystified — understand exactly why TMS over the left DLPFC reaches the subgenual cingulate, why ECT's electrode montage is an anatomical decision not a preference, and why VNS works from the bottom up • The autoimmune encephalitis differential — recognize anti-NMDA receptor encephalitis before the orofacial dyskinesias appear and initiate immunotherapy rather than a second antipsychotic • A 60-item board-style Master Compendium — consolidates every circuit-symptom pair from all 27 chapters into a single indexed drill resource aligned to the PRITE Clinical Neurosciences domain This book is written for psychiatry residents, fellows, and practicing psychiatrists who are done treating the brain as a black box and ready to practice with the anatomical clarity the field now demands. Every patient you see deserves a psychiatrist who can localize the problem — pick up this book and become that clinician.

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