Sir Isaac Newton — among the greatest mathematicians and natural philosophers of all time — devoted a substantial portion of his later years to theological and biblical studies. *Observations upon the Prophecies of Daniel, and the Apocalypse of St. John* was published posthumously in 1733, six years after his death. The book treats the prophetic books of Daniel and Revelation as a single coordinated prophetic system. This edition reproduces the standard public-domain text in full.