This volume constitutes the proceedings of the 16th JSAI International Symposia on Artificial Intelligence (JSAI-isAI), held in Hamamatsu, Japan, in May 2024.
The 21 full papers presented in this proceedings volume were carefully reviewed and selected from 63 submissions. The papers are organized in the following topical sections: AI-Biz 2024, BIAS 2024, JURISIN 2024, and SCIDOCA 2024.