This book serves as a reference for researchers and practitioners in academia and industry. Smart education, smart e-learning and smart pedagogy are emerging and rapidly growing areas that have a potential to transform existing teaching strategies, learning environments and educational activities and technology. They are focused at enabling instructors to develop innovative ways of achieving excellence in teaching in highly technological smart university and providing students with new opportunities to maximize their success using smart classrooms, smart systems and technology. This book contains the contributions presented at the 9th international KES conference on Smart Education and e-Learning (SEEL-2022) with the Smart Pedagogy as the main conference theme. It comprises of forty nine high-quality peer-reviewed papers that are grouped into several interconnected parts: Part 1—Smart Pedagogy, Part 2—Smart Education, Part 3—Smart e-Learning, Part 4—Smart University, Part 5—Smart Education: Systems and Technology, Part 6—Digital Humanities and Social Sciences for Smart University Development: the Innovative Methods, Models and Technologies, Part 7—Digital Transformation of Education and Economics in Smart University and Part 8—Smart Education for Children with Special Educational Needs. We believe this book will serve as a useful source of research data and valuable information for faculty, scholars, Ph.D. students, administrators and practitioners—those who are interested in smart education, smart e-learning and smart pedagogy.