Background. A prospective randomised controlled trial comparing gamete intrafallopian transfer (GIFT) with intrauterine insemination (IUI) was undertaken at the Fertility and Reproductive Biology Unit of the Department of Obstetrics and Gynaecology, Tygerberg Hospital, between July 1999 and June 2000. Method. Eighty-five women were included in the study and were randomly allocated between the two groups after routine infertility investigations, 41 women to IUI and 44 women to GIFT. A combination of clomiphene citrate and human menopausal gonadotropin was administered to both groups to achieve ovulation.
