This book contains the latest computational intelligence methodologies and applications. This book is a collection of selected papers presented at International Conference on Sustainable Computing and Intelligent Systems (SCIS 2021), held in Jaipur, India, during February 5–6, 2021. It includes novel and innovative work from experts, practitioners, scientists, and decision-makers from academia and industry. It covers selected papers in the area of artificial intelligence and intelligent systems, intelligent business systems, machine intelligence, computer vision, Web intelligence, big data analytics, swarm intelligence, and related topics.