This book highlights a collection of high-quality peer-reviewed research papers presented at the Sixth International Conference on Information System Design and Intelligent Applications (INDIA 2019), held at Lendi Institute of Engineering & Technology, Vizianagaram, Andhra Pradesh, India, from 1 to 2 November 2019. It covers a wide range of topics in computer science and information technology, from wireless networks, social networks, wireless sensor networks, information and network security, to web security, Internet of Things, bioinformatics, geoinformatics and computer networks.