This book constitutes the proceedings of the 17th International Conference on Web Information Systems and Applications, WISA 2020, held in Guangzhou, China, in September 2020. The 42 full papers and 16 short papers presented were carefully reviewed and selected from 165 submissions. The papers are grouped in topical sections on world wide web, recommendation, query processing and algorithm, natural language processing, machine learning, graph query, edge computing and data mining, data privacy and security, and blockchain.