This book includes high-quality papers presented at the Symposium 2019, organised by Sikkim Manipal Institute of Technology (SMIT), in Sikkim from 26–27 February 2019. It discusses common research problems and challenges in medical image analysis, such as deep learning methods. It also discusses how these theories can be applied to a broad range of application areas, including lung and chest x-ray, breast CAD, microscopy and pathology. The studies included mainly focus on the detection of events from biomedical signals.