Family Secrets is a medical mystery/love story set in New York City. A New York senator, who hopes to be the next US president, is shot while speaking at a fundraiser. He is rushed to the hospital, but dies as a result of an allergic reaction to the anesthesia he receives. An investigation is launched as to why the treating anesthesiologist, recently recruited by the hospital, failed to see the medical chart entry indicating an allergy to certain anesthesia. Over time, the anesthesiologist develops a relationship with the hospital's chief neonatologist, who previously had a relationship with the dead senator. But family secrets are revealed as the ultimate cause of the senator's death.